Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T07087 | Target Info | |||
Target Name | Focal adhesion kinase 2 (PTK2B) | ||||
Synonyms |
Related adhesion focal tyrosine kinase; RAFTK; Protein-tyrosine kinase 2-beta; Proline-rich tyrosine kinase 2; PYK2; FAK2; FADK 2; Cell adhesion kinase beta; Calcium-regulated non-receptor proline-rich tyrosine kinase; Calcium-dependent tyrosine kinase; CAKB; CAK-beta; CADTK
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Target Type | Literature-reported Target | ||||
Gene Name | PTK2B | ||||
Biochemical Class | Kinase | ||||
UniProt ID |
Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
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Compound Name |
1-[5-Tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[5-(hydroxymethyl)-1H-pyrazol-3-yl]urea
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2207442; BDBM50403009
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Activity |
IC50 ~ 100000 nM
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[1] |
References | Top | ||||
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REF 1 | Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7523-9. |
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