Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T04123 | Target Info | |||
| Target Name | Serine/threonine-protein phosphatase 5 (PPP5C) | ||||
| Synonyms |
Protein phosphatase T; PPT protein; PPP5; PP5; PP-T
Click to Show/Hide
|
||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | PPP5C | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 4 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3609375; SCHEMBL18281593; BDBM50112357
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3609373; SCHEMBL18281622; BDBM50112356; IC1=CC=C(C=C1)NC(C(=O)NC1=CC=C(C=C1)NC(C(S(=O)(=O)O)C1=CC=CC=C1)=O)=O
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2-Hydroxy-4-[1-(cyclohexylcarbamoyl)pentyloxy]-5-[2-(trifluoromethoxy)phenylethynyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3426913; BDBM50087856
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3609374; SCHEMBL18289745; BDBM50112358
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Cefsulodin sodium salt
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3351077; BDBM50282169; SDCCGSBI-0050247.P002
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. ACS Med Chem Lett. 2015 Jun 8;6(7):782-6. | ||||
| REF 2 | A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem. 2015 Jun 15;23(12):2798-809. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.