Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T03529 | Target Info | |||
| Target Name | Regulator of G-protein signaling 8 (RGS8) | ||||
| Synonyms |
RGS8
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| Target Type | Patented-recorded Target | ||||
| Gene Name | RGS8 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 6 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-Tert-butyl-4-methyl-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037361; SCHEMBL13517153; BDBM50384753
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| Activity |
IC50 = 56000 nM
|
[1] | |||
| Compound Name |
2-Ethyl-4-(2-methylpropyl)-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037366; SCHEMBL13517328; BDBM50384768
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| Activity |
IC50 = 70600 nM
|
[1] | |||
| Compound Name |
2-Butyl-4-(2-methylpropyl)-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037367; SCHEMBL13516736; BDBM50384769
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| Activity |
IC50 = 98000 nM
|
[1] | |||
| Compound Name |
4-Butyl-2-tert-butyl-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037364; SCHEMBL13516875; BDBM50384766
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| Activity |
IC50 = 119000 nM
|
[1] | |||
| Compound Name |
2,4-Dibutyl-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037363; SCHEMBL11455650; BDBM50384765
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| Activity |
IC50 = 122000 nM
|
[1] | |||
| Compound Name |
2-Tert-butyl-4-(2-methylpropyl)-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037368; SCHEMBL13517035; BDBM50384770
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|
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| Activity |
IC50 = 194000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-[(4-Methoxyphenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2037355; SCHEMBL13517756; BDBM50384758
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| Activity |
IC50 = 312000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett. 2012 Feb 9;3(2):146-150. | ||||
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