Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T00973 | Target Info | |||
| Target Name | Polybromo-1 (PBRM1) | ||||
| Synonyms |
hPB1; Protein polybromo-1; Polybromo-1D; PB1; BRG1-associated factor 180; BAF180
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| Target Type | Literature-reported Target | ||||
| Gene Name | PBRM1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 4 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N,2-Dimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1513201; HMS1919G18; ZINC1431623; BDBM50495427; STK499824; AKOS000667010; MCULE-6004134216; NCGC00141995-01; N,2-Dimethyl-5-(3-methyl-1,2,4-triazolo[3,4-a]phthalazine-6-yl)benzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N,N,2-Trimethyl-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3108781; ZINC1431624; BDBM50495429; STK796216; AKOS000667011; MCULE-3420882507; N,N,2-trimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]methanesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110357; ZINC5303354; BDBM50495428; STK796556; AKOS005612901; MCULE-8228444058; N-[2-Methyl-5-(3-methyl-1,2,4-triazolo[3,4-a]phthalazine-6-yl)phenyl]methanesulfonamide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]propanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3108806; ZINC5306176; BDBM50495432; STK592391; AKOS005514326; MCULE-7491487388
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | [1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains. J Med Chem. 2014 Jan 23;57(2):462-76. | ||||
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