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| Protein General Information |
Top |
| Full Name |
TNF receptor-associated factor 4 (TRAF4)
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| UniProt ID |
TRAF4_HUMAN
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| Gene Name |
TRAF4
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| Gene ID |
9618
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Low-affinity nerve growth factor receptor (NGFR) |
Target Info
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PPI Info
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[1] |
| Interacting Preclinical Target(s) |
Herpesvirus ubiquitin-specific protease (HAUSP) |
Target Info
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PPI Info
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[2] |
| Interacting Literature-reported Target(s) |
Neutrophil cytosol factor 1 (NCF1) |
Target Info
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PPI Info
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[3] |
| References |
Top |
| REF 1 |
TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction. J Biol Chem. 1999 Oct 15;274(42):30202-8.
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| REF 2 |
SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 1;27(3):274-87.
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| REF 3 |
Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase. J Biol Chem. 2002 Aug 2;277(31):28051-7.
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