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| Protein General Information |
Top |
| Full Name |
Talin-1 (TLN1)
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| UniProt ID |
TLN1_HUMAN
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| Gene Name |
TLN1
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| Gene ID |
7094
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| Interacting TTD Target Information |
Top |
| Interacting Clinical trial Target(s) |
Integrin alpha-4/beta-1 (ITGA4/B1) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Integrin beta-3 (ITGB3) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides. J Biol Chem. 2001 Jun 15;276(24):21217-27.
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| REF 2 |
Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding functions. The talin n-terminal head domain interacts with the membrane-proximal region of the beta(3) cytoplasmic tail. J Biol Chem. 1999 Oct 1;274(40):28575-83.
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