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| Protein General Information |
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| Full Name |
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1)
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| UniProt ID |
S61A1_HUMAN
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| Gene Name |
SEC61A1
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| Gene ID |
29927
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Endoplasmic reticulum chaperone BiP (HSPA5) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus. J Biol Chem. 2010 Dec 3;285(49):38720-9.
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| REF 2 |
Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum. J Biol Chem. 2015 Jul 24;290(30):18621-35.
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