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| Protein General Information |
Top |
| Full Name |
Double-strand break repair protein MRE11 (MRE11)
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| UniProt ID |
MRE11_HUMAN
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| Gene Name |
MRE11A
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| Gene ID |
4361
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
ATM serine/threonine kinase (ATM) |
Target Info
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PPI Info
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[1] |
| Interacting Literature-reported Target(s) |
Gamma-Histone H2AX (H2AFX) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature. 2005 Mar 31;434(7033):605-11.
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| REF 2 |
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J. 2004 Jul 7;23(13):2674-83.
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