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| Protein General Information (TTD Target) |
Top |
| Full Name |
AP endonuclease 1 (APEX1)
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Clinical trial
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Target Info
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| UniProt ID |
APEX1_HUMAN
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| Gene Name |
APEX1
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| Gene ID |
328
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
|
PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
Histone acetyltransferase p300 (EP300) |
Target Info
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PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Importance of EGFR/ERCC1 interaction following radiation-induced DNA damage. Clin Cancer Res. 2014 Jul 1;20(13):3496-506.
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| REF 2 |
Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. Oncogene. 2011 Jan 27;30(4):482-93.
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