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Target General Information |
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Target ID |
T98269 |
Target Info
|
Target Name |
Caspase-1 (CASP1) |
Synonyms |
P45; Interleukin-1 beta-converting enzyme; Interleukin-1 beta converting enzyme; Interleukin-1 beta convertase; IL1BCE; IL1BC; IL-1BC; IL-1 beta-converting enzyme; IL-1 beta converting enzyme; ICE; CASP-1 |
Target Type |
Clinical trial Target |
Gene Name |
CASP1 |
Biochemical Class |
Peptidase |
UniProt ID |
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Patent(s) and the Corresponding Patented Drug(s) |
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World Intellectual Property Organization (WIPO) |
Patent ID |
WO2015144183 |
Title |
Treatment of Contact Dermatitis. |
Abstract |
The present invention provides a method for treating contact dermatitis by the topical administration of a caspase-1 inhibitor. The present invention further provides a pharmaceutical composition comprising a caspase-1 inhibitor for the treatment of contact dermatitis. |
Applicant(s) |
University of Copenhagen |
Representative Drug(s) |
D04KIH |
Drug Info
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N.A. |
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[1] |
2
|
D07AVV
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Drug Info
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N.A.
|
[1] |
United States Patent and Trademark Office (USPTO) |
Patent ID |
US20140011847 |
Title |
Caspase Inhibitors and Uses Thereof. |
Patent ID |
US9045524 |
Title |
Selective Caspase Inhibitors and Uses Thereof. |
References |
Top |
REF 1 |
Caspase inhibitors: a review of recently patented compounds (2013-2015).Expert Opin Ther Pat. 2018 Jan;28(1):47-59.
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