Target and Its Patented Drug(s)

Content Navigation (  All   None )                                      
Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T94880 Target Info
Target Name TYRO3 tyrosine kinase receptor (TYRO3)
Synonyms Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase TIF; Tyrosine-protein kinase SKY; Tyrosine-protein kinase RSE; Tyrosine-protein kinase DTK; Tyrosine-protein kinase BYK; TIF; SKY; RSE; DTK; BYK
Target Type Clinical trial Target
Gene Name TYRO3
UniProt ID
TYRO3_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9708333
Title Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors
Abstract This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
Applicant(s) Incyte Corporation
Patent ID US9708333
Title Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors
Abstract This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
Applicant(s) Incyte Corporation
Patent ID US9708333
Title Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors
Abstract This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
Applicant(s) Incyte Corporation
Patent ID US9649309
Title Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity
Abstract Uses of pyrimidines with anti-Mer tyrosine kinase activity as anti-infective agents, immunostimulatory and immunomodulatory agents, anti-cancer agents (including against MerTK?/? tumors and ITD and TKD mutant forms of Acute Myeloid Leukemia (AML)), and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.
Applicant(s) The University of North Carolina at Chapel Hill
Representative Drug(s) D08OEW Drug Info IC50 = 2799 nM Click to Show More [2]
2 D03RHV Drug Info IC50 = 19187 nM [2]
3 D0M9TR Drug Info IC50 = 19943 nM [2]
Patent ID US9649309
Title Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity
Abstract Uses of pyrimidines with anti-Mer tyrosine kinase activity as anti-infective agents, immunostimulatory and immunomodulatory agents, anti-cancer agents (including against MerTK?/? tumors and ITD and TKD mutant forms of Acute Myeloid Leukemia (AML)), and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.
Applicant(s) The University of North Carolina at Chapel Hill
Representative Drug(s) D08OEW Drug Info IC50 = 2799 nM Click to Show More [2]
2 D03RHV Drug Info IC50 = 19187 nM [2]
3 D0M9TR Drug Info IC50 = 19943 nM [2]
Patent ID US9649309
Title Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity
Abstract Uses of pyrimidines with anti-Mer tyrosine kinase activity as anti-infective agents, immunostimulatory and immunomodulatory agents, anti-cancer agents (including against MerTK?/? tumors and ITD and TKD mutant forms of Acute Myeloid Leukemia (AML)), and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.
Applicant(s) The University of North Carolina at Chapel Hill
Representative Drug(s) D08OEW Drug Info IC50 = 2799 nM Click to Show More [2]
2 D03RHV Drug Info IC50 = 19187 nM [2]
3 D0M9TR Drug Info IC50 = 19943 nM [2]
Patent ID US10053465
Title Pyrrolopyrimidine derivatives as TAM inhibitors
Abstract This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
Applicant(s) Incyte Corporation
Patent ID US10053465
Title Pyrrolopyrimidine derivatives as TAM inhibitors
Abstract This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
Applicant(s) Incyte Corporation
Patent ID US10053465
Title Pyrrolopyrimidine derivatives as TAM inhibitors
Abstract This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
Applicant(s) Incyte Corporation
References  Top
REF 1 Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors. US9708333.
REF 2 Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity. US9649309.
REF 3 Pyrrolopyrimidine derivatives as TAM inhibitors. US10053465.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.