Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T94449 | Target Info | |||
| Target Name | Protein-tyrosine phosphatase eta (HPTP) | ||||
| Synonyms | Receptor-type tyrosine-protein phosphatase eta; R-PTP-eta; R-PTP-J; Protein-tyrosine phosphatase receptor type J; HPTP eta; Density-enhanced phosphatase 1; DEP1; DEP-1; CD148 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | PTPRJ | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| United States Patent and Trademark Office (USPTO) | |||||
| Patent ID | US9340574 | ||||
| Title | Inhibitors of protein tyrosine phosphatases | ||||
| Abstract | Novel protein tyrosine phosphatase (PTP) inhibitor compounds synthesized from phosphonodifluoromethyl phenylalanine (F2Pmp) are provided. Use of these compounds for inhibiting a PTP enzyme (such as PTP-MEG2), as well as treating a disease, disorder, or condition associated with inappropriate activity of a PTP (such as type 2 diabetes), is also provided. | ||||
| Applicant(s) | Indiana University Research and Technology Corporation | ||||
| Representative Drug(s) | D0H6LK | Drug Info | IC50 > 10000nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Inhibitors of protein tyrosine phosphatases. US9340574. | ||||
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