Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T94201 Target Info
Target Name SRSF protein kinase 1 (SRPK1)
Synonyms Serine/arginine-rich protein-specific kinase 1; SR-protein-specific kinase 1; SFRS protein kinase 1
Target Type Preclinical Target
Gene Name SRPK1
Biochemical Class Kinase
UniProt ID
SRPK1_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9695160
Title Piperazine derivatives for treating disorders
Abstract Anti-angiogenic treatments, treatments of hyperpermeability disorders, treatments of neuropathic and neurodegenerative disorders, pain treatments, methods of reducing the risk of pre-eclampsia and compounds for use in such methods are described.
Applicant(s) The University of Nottingham; NewSouth Innovations PTY Limited
Representative Drug(s) D0NY4A Drug Info IC50 = 55 nM Click to Show More [1]
2 D0LA9D Drug Info IC50 = 440 nM [1]
3 D03OBN Drug Info IC50 = 4688 nM [1]
Patent ID US9695160
Title Piperazine derivatives for treating disorders
Abstract Anti-angiogenic treatments, treatments of hyperpermeability disorders, treatments of neuropathic and neurodegenerative disorders, pain treatments, methods of reducing the risk of pre-eclampsia and compounds for use in such methods are described.
Applicant(s) The University of Nottingham; NewSouth Innovations PTY Limited
Representative Drug(s) D0NY4A Drug Info IC50 = 55 nM Click to Show More [1]
2 D0LA9D Drug Info IC50 = 440 nM [1]
3 D03OBN Drug Info IC50 = 4688 nM [1]
Patent ID US9695160
Title Piperazine derivatives for treating disorders
Abstract Anti-angiogenic treatments, treatments of hyperpermeability disorders, treatments of neuropathic and neurodegenerative disorders, pain treatments, methods of reducing the risk of pre-eclampsia and compounds for use in such methods are described.
Applicant(s) The University of Nottingham; NewSouth Innovations PTY Limited
Representative Drug(s) D0NY4A Drug Info IC50 = 55 nM Click to Show More [1]
2 D0LA9D Drug Info IC50 = 440 nM [1]
3 D03OBN Drug Info IC50 = 4688 nM [1]
References  Top
REF 1 Piperazine derivatives for treating disorders. US9695160.

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