Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T82262 Target Info
Target Name Calmodulin-dependent kinase II (CAMKK2)
Synonyms KIAA0787; Calcium/calmodulin-dependent protein kinase kinase beta; Calcium/calmodulin-dependent protein kinase kinase 2; CaMKK beta; CaMKK 2; CaM-kinase kinase beta; CaM-kinase kinase 2; CaM-KK beta; CaM-KK 2; CAMKKB
Target Type Patented-recorded Target
Gene Name CAMKK2
Biochemical Class Kinase
UniProt ID
KKCC2_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9623028
Title Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof
Abstract Provided herein are methods for treating or preventing a cancer, in particular solid tumors and hematological cancers, comprising administering to a subject in need thereof an effective amount of a compound of formula (I):
Applicant(s) Signal Pharmaceuticals, LLC
Representative Drug(s) D0XF1S Drug Info IC50 = 34 nM Click to Show More [1]
2 D01UIJ Drug Info IC50 = 501 nM [1]
3 D0PO8N Drug Info IC50 = 728 nM [1]
Patent ID US9623028
Title Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof
Abstract Provided herein are methods for treating or preventing a cancer, in particular solid tumors and hematological cancers, comprising administering to a subject in need thereof an effective amount of a compound of formula (I):
Applicant(s) Signal Pharmaceuticals, LLC
Representative Drug(s) D0XF1S Drug Info IC50 = 34 nM Click to Show More [1]
2 D01UIJ Drug Info IC50 = 501 nM [1]
3 D0PO8N Drug Info IC50 = 728 nM [1]
Patent ID US9623028
Title Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof
Abstract Provided herein are methods for treating or preventing a cancer, in particular solid tumors and hematological cancers, comprising administering to a subject in need thereof an effective amount of a compound of formula (I):
Applicant(s) Signal Pharmaceuticals, LLC
Representative Drug(s) D0XF1S Drug Info IC50 = 34 nM Click to Show More [1]
2 D01UIJ Drug Info IC50 = 501 nM [1]
3 D0PO8N Drug Info IC50 = 728 nM [1]
References  Top
REF 1 Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof. US9623028.

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