Target and Its Patented Drug(s)

Content Navigation (  All   None )                                      
Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T71367 Target Info
Target Name MEK kinase kinase 4 (MAP4K4)
Synonyms Nckinteracting kinase; Nck-interacting kinase; Mitogenactivated protein kinase kinase kinase kinase 4; Mitogen-activated protein kinase kinase kinase kinase 4; MEKKK 4; MAPK/ERK kinase kinase kinase 4; KIAA0687; HPK/GCKlike kinase HGK; HPK/GCK-like kinase HGK; HGK
Target Type Patented-recorded Target
Gene Name MAP4K4
Biochemical Class Kinase
UniProt ID
M4K4_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9592235
Title Aminoquinazoline and pyridopyrimidine derivatives
Abstract The invention provides a method of treating cancer in a patient by administering a compound of formula (I): wherein R1 R2 and R3 are as defined herein, compositions including the compounds and methods of using the compounds.
Applicant(s) Genentech, Inc.
Representative Drug(s) D0HK8C Drug Info IC50 = 81.2 nM Click to Show More [1]
2 D00SDR Drug Info IC50 = 591 nM [1]
3 D0L2FW Drug Info IC50 = 751 nM [1]
Patent ID US9592235
Title Aminoquinazoline and pyridopyrimidine derivatives
Abstract The invention provides a method of treating cancer in a patient by administering a compound of formula (I): wherein R1 R2 and R3 are as defined herein, compositions including the compounds and methods of using the compounds.
Applicant(s) Genentech, Inc.
Representative Drug(s) D0HK8C Drug Info IC50 = 81.2 nM Click to Show More [1]
2 D00SDR Drug Info IC50 = 591 nM [1]
3 D0L2FW Drug Info IC50 = 751 nM [1]
Patent ID US9592235
Title Aminoquinazoline and pyridopyrimidine derivatives
Abstract The invention provides a method of treating cancer in a patient by administering a compound of formula (I): wherein R1 R2 and R3 are as defined herein, compositions including the compounds and methods of using the compounds.
Applicant(s) Genentech, Inc.
Representative Drug(s) D0HK8C Drug Info IC50 = 81.2 nM Click to Show More [1]
2 D00SDR Drug Info IC50 = 591 nM [1]
3 D0L2FW Drug Info IC50 = 751 nM [1]
References  Top
REF 1 Aminoquinazoline and pyridopyrimidine derivatives. US9592235.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.