Target and Its Patented Drug(s)

Content Navigation (  All   None )                                      
Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T64597 Target Info
Target Name Integrin beta-8 (ITGB8)
Synonyms Integrin subunit beta 8
Target Type Clinical trial Target
Gene Name ITGB8
Biochemical Class Integrin
UniProt ID
ITB8_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US10035778
Title Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
Abstract The present disclosure provides pharmaceutical agents of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods of using the pharmaceutical agents for the treatment of a variety of diseases and disorders are also provided.
Applicant(s) Saint Louis University
Representative Drug(s) D0QG9P Drug Info IC50 = 0.3 nM Click to Show More [1]
2 D04KXV Drug Info IC50 = 0.3 nM [1]
3 D0UB5E Drug Info IC50 = 0.7 nM [1]
Patent ID US10035778
Title Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
Abstract The present disclosure provides pharmaceutical agents of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods of using the pharmaceutical agents for the treatment of a variety of diseases and disorders are also provided.
Applicant(s) Saint Louis University
Representative Drug(s) D0QG9P Drug Info IC50 = 0.3 nM Click to Show More [1]
2 D04KXV Drug Info IC50 = 0.3 nM [1]
3 D0UB5E Drug Info IC50 = 0.7 nM [1]
Patent ID US10035778
Title Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
Abstract The present disclosure provides pharmaceutical agents of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods of using the pharmaceutical agents for the treatment of a variety of diseases and disorders are also provided.
Applicant(s) Saint Louis University
Representative Drug(s) D0QG9P Drug Info IC50 = 0.3 nM Click to Show More [1]
2 D04KXV Drug Info IC50 = 0.3 nM [1]
3 D0UB5E Drug Info IC50 = 0.7 nM [1]
References  Top
REF 1 Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists. US10035778.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.