Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T63846 Target Info
Target Name IL-1 receptor-associated kinase 1 (IRAK1)
Synonyms Interleukin-1 receptor-associated kinase 1; IRAK-1; IRAK
Target Type Patented-recorded Target
Gene Name IRAK1
Biochemical Class Kinase
UniProt ID
IRAK1_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
World Intellectual Property Organization (WIPO)
Patent ID WO2012084704
Title Indazolyl Triazole Derivatives As Irak Inhibitors.
Abstract Compounds of Formula (I) are used for the treatment of inflammation and autoimmune disorders.
Applicant(s) Merck Serono S.A
Representative Drug(s) D0NT8U Drug Info IC50 = 100 nM Click to Show More [1]
2 D0O6GQ Drug Info IC50 < 100 nM [1]
References  Top
REF 1 Inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4): a patent review (2012-2015).Expert Opin Ther Pat. 2016 Aug;26(8):917-32.

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