Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T63220 Target Info
Target Name Activated CDC42 kinase 1 (ACK-1)
Synonyms Tyrosine kinase non-receptor protein 2; ACK1; ACK-1
Target Type Patented-recorded Target
Gene Name TNK2
Biochemical Class Kinase
UniProt ID
ACK1_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9416123
Title Kinase modulators for the treatment of cancer
Abstract Compounds of the substituted pyrazole class as treatments for cancer are reported. A method of treating cancer in which a compound that inhibits the activity of receptor kinases. Said method is effective and can be provided in addition to standard therapies, notably chemotherapy using cytotoxic drugs and other forms of immune therapy including therapeutic vaccines.
Applicant(s) Synovo GmbH
Patent ID US9416123
Title Kinase modulators for the treatment of cancer
Abstract Compounds of the substituted pyrazole class as treatments for cancer are reported. A method of treating cancer in which a compound that inhibits the activity of receptor kinases. Said method is effective and can be provided in addition to standard therapies, notably chemotherapy using cytotoxic drugs and other forms of immune therapy including therapeutic vaccines.
Applicant(s) Synovo GmbH
Patent ID US8481733
Title Substituted imidazopyr- and imidazotri-azines
Abstract Fused pyridine-based bicyclic compounds having the structure of Formula I, as defined herein, pharmaceutically acceptable salts thereof, preparation, compositions, and disease treatment therewith. This abstract does not define or limit the invention.
Applicant(s) OSI Pharmaceuticals, LLC
Representative Drug(s) D0SZ3I Drug Info IC50 = 216.1 nM Click to Show More [2]
2 D0PX1D Drug Info IC50 = 233.8 nM [2]
3 D0T9JA Drug Info IC50 = 451 nM [2]
Patent ID US8481733
Title Substituted imidazopyr- and imidazotri-azines
Abstract Fused pyridine-based bicyclic compounds having the structure of Formula I, as defined herein, pharmaceutically acceptable salts thereof, preparation, compositions, and disease treatment therewith. This abstract does not define or limit the invention.
Applicant(s) OSI Pharmaceuticals, LLC
Representative Drug(s) D0SZ3I Drug Info IC50 = 216.1 nM Click to Show More [2]
2 D0PX1D Drug Info IC50 = 233.8 nM [2]
3 D0T9JA Drug Info IC50 = 451 nM [2]
Patent ID US8481733
Title Substituted imidazopyr- and imidazotri-azines
Abstract Fused pyridine-based bicyclic compounds having the structure of Formula I, as defined herein, pharmaceutically acceptable salts thereof, preparation, compositions, and disease treatment therewith. This abstract does not define or limit the invention.
Applicant(s) OSI Pharmaceuticals, LLC
Representative Drug(s) D0SZ3I Drug Info IC50 = 216.1 nM Click to Show More [2]
2 D0PX1D Drug Info IC50 = 233.8 nM [2]
3 D0T9JA Drug Info IC50 = 451 nM [2]
References  Top
REF 1 Kinase modulators for the treatment of cancer. US9416123.
REF 2 Substituted imidazopyr- and imidazotri-azines. US8481733.

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