Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T53524 Target Info
Target Name Platelet-derived growth factor receptor alpha (PDGFRA)
Synonyms RHEPDGFRA; Platelet-derived growth factor receptor 2; Platelet-derived growth factor alpha receptor; PDGFR2; PDGFR-alpha; PDGFR-2; PDGF-R-alpha; CD140a antigen; CD140a; CD140 antigen-like family member A; Alpha-type platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor
Target Type Successful Target
Gene Name PDGFRA
Biochemical Class Kinase
UniProt ID
PGFRA_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
World Intellectual Property Organization (WIPO)
Patent ID WO2015112941
Title Novel Methods for Treating Cancer.
Abstract The invention provides thiazole-substituted indolin-2-ones as inhibitors of cancer stem cell pathway kinases (CSCPK) and related kinases, and methods of using these compounds, to treat subjects in need thereof.
Applicant(s) Boston Biomedical, Inc
Representative Drug(s) D0IH3I Drug Info IC50 = 4 to 30 nM [1]
United States Patent and Trademark Office (USPTO)
Patent ID US9029386
Title Inhibitors of Kinase Activity.
Applicant(s) Ym Biosciences Australia Pty
Representative Drug(s) D0AK1F Drug Info N.A. Click to Show More [2]
2 D0NB1V Drug Info N.A. [2]
3 D0O0AW Drug Info N.A. [2]
4 D0O4TA Drug Info N.A. [2]
5 D0T7BE Drug Info N.A. [2]
Patent ID US20130137660
Title Inhibitors of Kinase Activity.
Applicant(s) Ym Biosciences Australia Pty
Representative Drug(s) D0AK1F Drug Info N.A. Click to Show More [2]
2 D0NB1V Drug Info N.A. [2]
3 D0O0AW Drug Info N.A. [2]
4 D0O4TA Drug Info N.A. [2]
5 D0T7BE Drug Info N.A. [2]
Patent ID US9187454
Title Inhibitors of Kinases and Cancer Stem Cells, and Methods of Preparation and Use Thereof.
Representative Drug(s) D0IH3I Drug Info IC50 = 4 to 30 nM [1]
Patent ID US8299106
Title Compositions of Kinase Inhibitors and Their Use for Treatment of Cancer and Other Diseases Related To Kinases.
Representative Drug(s) D0IH3I Drug Info IC50 = 4 to 30 nM [1]
References  Top
REF 1 Cancer stem cell (CSC) inhibitors: a review of recent patents (2012-2015).Expert Opin Ther Pat. 2017 Jul;27(7):753-761.
REF 2 RET kinase inhibitors: a review of recent patents (2012-2015).Expert Opin Ther Pat. 2017 Jan;27(1):91-99.

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