Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T52624 | Target Info | |||
| Target Name | Platelet-derived growth factor receptor (PDGFR) | ||||
| Synonyms | Platelet-derived growth factor receptor tyrosine kinase; PDGFR kinase; PDGF-R | ||||
| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| World Intellectual Property Organization (WIPO) | |||||
| Patent ID | WO2014132220 | ||||
| Title | Solid forms of Bicyclic Heterocyclic Derivatives As Pdgf Receptor Mediators. | ||||
| Abstract | The present invention provides novel solid forms of pharmaceutically active agents and therapeutic uses thereof. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. | ||||
| Applicant(s) | Novartis Ag | ||||
| Representative Drug(s) | D0Z4QJ | Drug Info | IC50 = 3 nM | Click to Show More | [1] |
| 2 | D0S6IA | Drug Info | IC50 = 45 nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Evaluation of WO-2014132220, selective PDGFR inhibitors for the treatment of pulmonary arterial hypertension.Expert Opin Ther Pat. 2015 Apr;25(4):493-9. | ||||
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