Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T52297 Target Info
Target Name Oxysterols receptor LXR-alpha (NR1H3)
Synonyms Nuclear receptor subfamily 1 group H member 3; Nuclear receptor LXRalpha; Nuclear orphan receptor LXR-alpha; Liver X receptor alpha; LXRalpha; LXRA
Target Type Patented-recorded Target
Gene Name NR1H3
Biochemical Class Nuclear hormone receptor
UniProt ID
NR1H3_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9073931
Title Liver X receptor modulators
Abstract Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D07QYV Drug Info N.A. Click to Show More [1]
2 D03UAE Drug Info N.A. [1]
3 D0Y7ZA Drug Info N.A. [1]
Patent ID US9073931
Title Liver X receptor modulators
Abstract Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D07QYV Drug Info N.A. Click to Show More [1]
2 D03UAE Drug Info N.A. [1]
3 D0Y7ZA Drug Info N.A. [1]
Patent ID US9073931
Title Liver X receptor modulators
Abstract Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D07QYV Drug Info N.A. Click to Show More [1]
2 D03UAE Drug Info N.A. [1]
3 D0Y7ZA Drug Info N.A. [1]
Patent ID US9006244
Title Liver X receptor modulators
Abstract Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D0K8GC Drug Info N.A. Click to Show More [2]
2 D0U2EG Drug Info N.A. [2]
3 D07QIZ Drug Info N.A. [2]
Patent ID US9006244
Title Liver X receptor modulators
Abstract Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D0K8GC Drug Info N.A. Click to Show More [2]
2 D0U2EG Drug Info N.A. [2]
3 D07QIZ Drug Info N.A. [2]
Patent ID US9006244
Title Liver X receptor modulators
Abstract Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D0K8GC Drug Info N.A. Click to Show More [2]
2 D0U2EG Drug Info N.A. [2]
3 D07QIZ Drug Info N.A. [2]
Patent ID US10144715
Title Piperazine derivatives as liver X receptor modulators
Abstract Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D0TG1V Drug Info N.A. Click to Show More [3]
2 D0W1XE Drug Info N.A. [3]
3 D04XII Drug Info N.A. [3]
Patent ID US10144715
Title Piperazine derivatives as liver X receptor modulators
Abstract Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D0TG1V Drug Info N.A. Click to Show More [3]
2 D0W1XE Drug Info N.A. [3]
3 D04XII Drug Info N.A. [3]
Patent ID US10144715
Title Piperazine derivatives as liver X receptor modulators
Abstract Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.
Applicant(s) Vitae Pharmaceuticals, Inc.
Representative Drug(s) D0TG1V Drug Info N.A. Click to Show More [3]
2 D0W1XE Drug Info N.A. [3]
3 D04XII Drug Info N.A. [3]
References  Top
REF 1 Liver X receptor modulators. US9073931.
REF 2 Liver X receptor modulators. US9006244.
REF 3 Piperazine derivatives as liver X receptor modulators. US10144715.

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