Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T50224 | Target Info | |||
| Target Name | Ribosomal protein S6 kinase alpha-5 (RSK5) | ||||
| Synonyms | S6K-alpha-5; RSKL; RSK-like protein kinase; Nuclear mitogen- and stress-activated protein kinase 1; MSK1; 90 kDa ribosomal protein S6 kinase 5 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | RPS6KA5 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| United States Patent and Trademark Office (USPTO) | |||||
| Patent ID | US9365572 | ||||
| Title | PI3K and/or mTOR inhibitor | ||||
| Abstract | The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt, a stereoisomer or a solvate thereof, wherein R1, R2, R3, R4, X, Y, A and B are as defined in the specification. The present invention further relates to a method for preparing these compounds, a pharmaceutical composition containing these compounds, and a use of these compounds in manufacture of a medicament for treating and/or preventing proliferative diseases. | ||||
| Applicant(s) | Xuanzhu Pharma Co., Ltd. | ||||
| Representative Drug(s) | D0Y3AM | Drug Info | IC50 > 10000nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | PI3K and/or mTOR inhibitor. US9365572. | ||||
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