Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T45228 | Target Info | |||
| Target Name | Ghrelin O acyltransferase (GOAT) | ||||
| Synonyms | Oacyltransferase domaincontaining protein 4; OACT4; O-acyltransferase domain-containing protein 4; Membranebound Oacyltransferase domaincontaining protein 4; Membrane-bound O-acyltransferase domain-containing protein 4; Ghrelin Oacyltransferase; Ghrelin O-acyltransferase; FKSG89 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | MBOAT4 | ||||
| Biochemical Class | Acyltransferase | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| World Intellectual Property Organization (WIPO) | |||||
| Patent ID | WO2010039461 | ||||
| Title | Methods for Synthesis and Uses of Inhibitors of Ghrelin O-Acyltransferase As Potential Therapeutic Agents for Obesity and Diabetes. | ||||
| Abstract | The invention provides inhibitors of ghrelin O-acyltransferase, and methods of making and using them. In some embodiments, the invention provides bisubstrate analog inhibitors of ghrelin O-acyltransferase, which can be effective in treating, for example, obesity and diabetes mellitus. | ||||
| Applicant(s) | The Johns Hopkins University | ||||
| Representative Drug(s) | D0YY8N | Drug Info | N.A. | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.