Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T42247 | Target Info | |||
| Target Name | Melanoma inhibitor of apoptosis protein (ML-IAP) | ||||
| Synonyms | UNQ5800/PRO19607/PRO21344; RNF50; RING-type E3 ubiquitin transferase BIRC7; RING finger protein 50; MLIAP; Livin; Kidney inhibitor of apoptosis protein; KIAP; Baculoviral IAP repeat-containing protein 7 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | BIRC7 | ||||
| Biochemical Class | Acyltransferase | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| World Intellectual Property Organization (WIPO) | |||||
| Patent ID | WO2011082285 | ||||
| Title | Ligand-Directed Covalent Modification of Protein. | ||||
| Abstract | The present invention relates to enzyme inhibitors. More specifically, the present invention relates to ligand-directed covalent modification of proteins; method of designing same; pharmaceutical formulation of same; and method of use. | ||||
| Applicant(s) | Avila Therapeutics, Inc | ||||
| Representative Drug(s) | D09VAX | Drug Info | Ki < 1000 nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Small molecule inhibitor of apoptosis proteins antagonists: a patent review.Expert Opin Ther Pat. 2015 Jul;25(7):755-74. | ||||
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