| Patent(s) and the Corresponding Patented Drug(s) |
Top |
| World Intellectual Property Organization (WIPO) |
| Patent ID |
WO2013148426 |
| Title |
Microparticle Vaccine Against Malaria. |
| Abstract |
Multilayer films comprise polypeptide epitopes from Plasmodium falciparum, specifically a circumsporozoite T1, B or T* epitope. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films can include at least one designed peptide that includes one or more polypeptide epitopes from a Plasmodium protozoan. |
| Applicant(s) |
Artificial Cell Technologies, Inc |
| Representative Drug(s) |
D0H9SD |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2013119856 |
| Title |
Improved Adjuvant formulations Comprising Tlr4 Agonists and Methods of Using The Same. |
| Abstract |
Formulations and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed. The formulations generally comprise a TLR4 agonist and a metabolizable oil at a concentration of about 0.01%-1% v/v, wherein the hydrophobic:lipophilic balance (HLB) of the emusion is greater than about 9. |
| Applicant(s) |
Infectious Disease Research Institute |
| Representative Drug(s) |
D0QW0C |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2005070959 |
| Title |
Compositions Comprising Immune Response Altering Agents and Methods of Use. |
| Abstract |
The present invention relates to immune response enhancing agents that alter an immune response generated against a heterologous target molecule. Compositions and methods of use of said immune response enhancing agents are also provided. |
| Applicant(s) |
Mahairas, Gregory, G et al |
| Representative Drug(s) |
D0BW2B |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2015150568 |
| Title |
Novel Methods for Inducing An Immune Response. |
| Abstract |
Methods and uses are provided for inducing an immune response comprising at least two administrations of an immunogenic composition, wherein a lower dose is given in the second administration than in the first administration, and wherein the second administration may be unadjuvanted. |
| Applicant(s) |
Glaxosmithkline Biologicals Sa |
| Representative Drug(s) |
D08TOM |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2015091734 |
| Title |
Novel Malaria Vaccines. |
| Abstract |
The present invention relates to novel compositions for the immunisation against malaria as well as to uses of such compositions and to methods for producing such compositions. In particular, the invention relates to an immunogenic composition comprising a CelTOS antigen and an adjuvant comprising an immunologically active saponin fraction. Optionally the adjuvant further comprises a TLR4 agonist. |
| Applicant(s) |
Glaxosmithkline Biologicals Sa United States Department of the Army |
| Representative Drug(s) |
D0T8XY |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2015035128 |
| Title |
Methods and Compositions for Viral Vectored Vaccines. |
| Abstract |
Methods and compositions are provided herein for non-invasive administration of an adenoviral vector (Ad-vector) vaccine with an adjuvant, such as a TLR3 agonist. These methods provide, for example, an increase in the immune response to the vaccine, an increase in the immunogenicity of the Ad-vector vaccine, an antigen sparing effect and improved safety with an effective protective immune response to the vaccine. |
| Applicant(s) |
Altimmune Inc |
| Representative Drug(s) |
D0K4CX |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2013148427 |
| Title |
Antigenic Compositions and Methods. |
| Abstract |
Multilayer films comprised of polypeptide epitopes and a toll-like receptor ligand. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films can include at least one designed peptide that includes one or more polypeptide epitopes from a virus, bacteria, fungus or parasite. |
| Applicant(s) |
Artificial Cell Technologies, Inc |
| Representative Drug(s) |
D0HK3A |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2009082440 |
| Title |
Compositions of Toll-Like Receptor Agonists and Malaria Antigens and Methods of Use. |
| Abstract |
Compositions that include at least one fusion protein that includes at least a portion of at least one Toll-like Receptor agonist and at least a portion of at least one malaria antigen can be employed in methods that stimulate an immune response in a subject, in particular, sterile immunity and a protective immune response in a subject. |
| Applicant(s) |
Vaxinnate Corporation |
| Representative Drug(s) |
D06IVC |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2008009652 |
| Title |
Vaccines for Malaria. |
| Abstract |
The present invention relates to a hybrid/ fusion protein derived from the CS protein of Plasmodium vivax (P. vivax), methods for preparing and purifying the same, its use in medicine, particularly in the prevention of malarial infections, for example those caused by P. vivax, compositions/vaccines containing the protein or antibodies against the protein such as monoclonal or polyclonal antibodies and use of the same, particularly in therapy. The invention also extends to lipoprotein particles of said hybrid protein and formulations/vaccines comprising the same and use thereof. In particular it relates to an immunogenic hybrid fusion protein comprising: a. at least one repeat unit derived from the repeating region of a type I circumsporozoite protein of P. vivax, b. at least one repeat unit derived from the repeating region of a type II circumsporozoite protein of P. vivax, and surface antigen S derived from Hepatitis B virus, or a fragment thereof. |
| Applicant(s) |
Glaxosmithkline Biologicals Sa the United States of America |
| Representative Drug(s) |
D0IH8R |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO200606195 |
| Title |
Detection/Measurement of Malaria Infection Disease Utilizing Natural Immunity By Hemozoin, Screening of Preventive of Therapeutic Medicine for Malaria Infection Disease & Regulation of Natural Immunity Induction. |
| Abstract |
Detection/Measurement of malaria infection disease utilizing Natural immunity by Hemozoin, screening of preventive of therapeutic medicine for malaria infection Disease and regulation of natural Immunity Induction. |
| Representative Drug(s) |
D0AF4V |
Drug Info
|
N.A. |
[1] |
| United States Patent and Trademark Office (USPTO) |
| Patent ID |
US20170128558 |
| Title |
Anti-Malaria Compositions and Methods. |
| Representative Drug(s) |
D0P8VT |
Drug Info
|
N.A. |
[1] |
