Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T13075 | Target Info | |||
| Target Name | Casein kinase I alpha (CSNK1A1) | ||||
| Synonyms | Casein kinase I isoform alpha; CKI-alpha; CK1 | ||||
| Target Type | Clinical trial Target | ||||
| Gene Name | CSNK1A1 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| United States Patent and Trademark Office (USPTO) | |||||
| Patent ID | US9096594 | ||||
| Title | Kinase inhibitors and methods of use thereof | ||||
| Abstract | The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3 or GSK3) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer. | ||||
| Applicant(s) | The Broad Institute, Inc.; The General Hospital Corporation; Dana-Farber Cancer Institute, Inc. | ||||
| Representative Drug(s) | D0MN6V | Drug Info | IC50 > 30000nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Kinase inhibitors and methods of use thereof. US9096594. | ||||
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