Target and Its Patented Drug(s)

Content Navigation (  All   None )                                      
Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T12241 Target Info
Target Name Cystathionine gamma-lyase (CTH)
Synonyms Gamma-cystathionase; Cysteine-protein sulfhydrase
Target Type Patented-recorded Target
Gene Name CTH
UniProt ID
CGL_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9725426
Title Cystathionine--lyase (CSE) inhibitors
Abstract Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine--lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Applicant(s) SOVA PHARMACEUTICALS, INC.
Representative Drug(s) D0BB4J Drug Info IC50 < 10000nM Click to Show More [1]
2 D06BHM Drug Info IC50 < 10000nM [1]
3 D0EC1A Drug Info IC50 = 55000 nM [1]
Patent ID US9725426
Title Cystathionine--lyase (CSE) inhibitors
Abstract Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine--lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Applicant(s) SOVA PHARMACEUTICALS, INC.
Representative Drug(s) D0BB4J Drug Info IC50 < 10000nM Click to Show More [1]
2 D06BHM Drug Info IC50 < 10000nM [1]
3 D0EC1A Drug Info IC50 = 55000 nM [1]
Patent ID US9725426
Title Cystathionine--lyase (CSE) inhibitors
Abstract Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine--lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Applicant(s) SOVA PHARMACEUTICALS, INC.
Representative Drug(s) D0BB4J Drug Info IC50 < 10000nM Click to Show More [1]
2 D06BHM Drug Info IC50 < 10000nM [1]
3 D0EC1A Drug Info IC50 = 55000 nM [1]
References  Top
REF 1 Cystathionine--lyase (CSE) inhibitors. US9725426.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.