Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T12081 Target Info
Target Name Phosphodiesterase 4C (PDE4C)
Synonyms cAMP-specific 3',5'-cyclic phosphodiesterase 4C; PDE21; DPDE1
Target Type Patented-recorded Target
Gene Name PDE4C
Biochemical Class Phosphoric diester hydrolase
UniProt ID
PDE4C_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9598421
Title Imidazopyridazine compounds
Abstract The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R3, R6, R7, and b are as defined herein. The invention is also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, and methods of preparing the compounds.
Applicant(s) Pfizer Inc.
Representative Drug(s) D0W5OE Drug Info IC50 = 64.9 nM Click to Show More [1]
2 D04VJX Drug Info IC50 = 208 nM [1]
3 D05TQB Drug Info IC50 = 326 nM [1]
Patent ID US9598421
Title Imidazopyridazine compounds
Abstract The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R3, R6, R7, and b are as defined herein. The invention is also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, and methods of preparing the compounds.
Applicant(s) Pfizer Inc.
Representative Drug(s) D0W5OE Drug Info IC50 = 64.9 nM Click to Show More [1]
2 D04VJX Drug Info IC50 = 208 nM [1]
3 D05TQB Drug Info IC50 = 326 nM [1]
Patent ID US9598421
Title Imidazopyridazine compounds
Abstract The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R3, R6, R7, and b are as defined herein. The invention is also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, and methods of preparing the compounds.
Applicant(s) Pfizer Inc.
Representative Drug(s) D0W5OE Drug Info IC50 = 64.9 nM Click to Show More [1]
2 D04VJX Drug Info IC50 = 208 nM [1]
3 D05TQB Drug Info IC50 = 326 nM [1]
References  Top
REF 1 Imidazopyridazine compounds. US9598421.

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