Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T11764 Target Info
Target Name Discoidin domain-containing receptor 2 (DDR2)
Synonyms Tyrosine-protein kinase TYRO10; Receptor protein-tyrosine kinase TKT; Neurotrophic tyrosine kinase, receptor-related 3; Discoidin domain-containing receptor tyrosine kinase 2; Discoidin domain receptor 2; DDR2; CD167 antigen-like family member B
Target Type Patented-recorded Target
Gene Name DDR2
Biochemical Class Kinase
UniProt ID
DDR2_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0CI3N Drug Info IC50 = 5 nM Click to Show More [1]
2 D05AFD Drug Info IC50 = 93 nM [1]
3 D0T8BO Drug Info IC50 = 181 nM [1]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0CI3N Drug Info IC50 = 5 nM Click to Show More [1]
2 D05AFD Drug Info IC50 = 93 nM [1]
3 D0T8BO Drug Info IC50 = 181 nM [1]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0CI3N Drug Info IC50 = 5 nM Click to Show More [1]
2 D05AFD Drug Info IC50 = 93 nM [1]
3 D0T8BO Drug Info IC50 = 181 nM [1]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0CI3N Drug Info IC50 = 5 nM Click to Show More [1]
2 D05AFD Drug Info IC50 = 93 nM [1]
3 D0T8BO Drug Info IC50 = 181 nM [1]
References  Top
REF 1 Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases. US9156852.

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