Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T11192 Target Info
Target Name ADAM metallopeptidase 33 (ADAM33)
Synonyms UNQ873/PRO1891; Disintegrin and metalloproteinase domain-containing protein 33; C20orf153; ADAM 33
Target Type Patented-recorded Target
Gene Name ADAM33
Biochemical Class Peptidase
UniProt ID
ADA33_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US8772478
Title Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
Abstract Benzenesulfonamide compounds having a structure of the following general formula (I) are described. Also described, are methods for synthesizing the compounds, and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
Applicant(s) Galderma Research & Development
Representative Drug(s) D0O1NA Drug Info IC50 = 181 nM Click to Show More [1]
2 D0NW8W Drug Info IC50 = 181 nM [1]
3 D02XAR Drug Info IC50 = 249 nM [1]
4 D0Z7FD Drug Info IC50 = 298 nM [1]
Patent ID US8772478
Title Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
Abstract Benzenesulfonamide compounds having a structure of the following general formula (I) are described. Also described, are methods for synthesizing the compounds, and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
Applicant(s) Galderma Research & Development
Representative Drug(s) D0O1NA Drug Info IC50 = 181 nM Click to Show More [1]
2 D0NW8W Drug Info IC50 = 181 nM [1]
3 D02XAR Drug Info IC50 = 249 nM [1]
4 D0Z7FD Drug Info IC50 = 298 nM [1]
Patent ID US8772478
Title Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
Abstract Benzenesulfonamide compounds having a structure of the following general formula (I) are described. Also described, are methods for synthesizing the compounds, and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
Applicant(s) Galderma Research & Development
Representative Drug(s) D0O1NA Drug Info IC50 = 181 nM Click to Show More [1]
2 D0NW8W Drug Info IC50 = 181 nM [1]
3 D02XAR Drug Info IC50 = 249 nM [1]
4 D0Z7FD Drug Info IC50 = 298 nM [1]
Patent ID US8772478
Title Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
Abstract Benzenesulfonamide compounds having a structure of the following general formula (I) are described. Also described, are methods for synthesizing the compounds, and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
Applicant(s) Galderma Research & Development
Representative Drug(s) D0O1NA Drug Info IC50 = 181 nM Click to Show More [1]
2 D0NW8W Drug Info IC50 = 181 nM [1]
3 D02XAR Drug Info IC50 = 249 nM [1]
4 D0Z7FD Drug Info IC50 = 298 nM [1]
References  Top
REF 1 Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics. US8772478.

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