Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T10118 Target Info
Target Name Chymotrypsin-C (CLCR)
Synonyms Caldecrin; CLCR
Target Type Patented-recorded Target
Gene Name CTRC
UniProt ID
CTRC_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9695194
Title Benzoxazinone derivatives for treatment of skin diseases
Abstract The present invention relates to methods and compositions for inhibiting the activity of skin proteases, especially human kallikrein 7 (KLK7), human kallikrein 5 (KLK5), and human kallikrein 14 (KLK14). More specifically, the invention relates to the use of substituted 3,1-benzoxazin-4-ones being selective inhibitors of human skin kallikreins for the treatment of skin diseases, more specifically for the treatment of inflammatory skins diseases, especially Netherton syndrome.
Applicant(s) SIXERA PHARMA AB
Representative Drug(s) D0P0OH Drug Info N.A. Click to Show More [1]
2 D01IXT Drug Info N.A. [1]
3 D00PVE Drug Info N.A. [1]
4 D05CJM Drug Info N.A. [1]
Patent ID US9695194
Title Benzoxazinone derivatives for treatment of skin diseases
Abstract The present invention relates to methods and compositions for inhibiting the activity of skin proteases, especially human kallikrein 7 (KLK7), human kallikrein 5 (KLK5), and human kallikrein 14 (KLK14). More specifically, the invention relates to the use of substituted 3,1-benzoxazin-4-ones being selective inhibitors of human skin kallikreins for the treatment of skin diseases, more specifically for the treatment of inflammatory skins diseases, especially Netherton syndrome.
Applicant(s) SIXERA PHARMA AB
Representative Drug(s) D0P0OH Drug Info N.A. Click to Show More [1]
2 D01IXT Drug Info N.A. [1]
3 D00PVE Drug Info N.A. [1]
4 D05CJM Drug Info N.A. [1]
Patent ID US9695194
Title Benzoxazinone derivatives for treatment of skin diseases
Abstract The present invention relates to methods and compositions for inhibiting the activity of skin proteases, especially human kallikrein 7 (KLK7), human kallikrein 5 (KLK5), and human kallikrein 14 (KLK14). More specifically, the invention relates to the use of substituted 3,1-benzoxazin-4-ones being selective inhibitors of human skin kallikreins for the treatment of skin diseases, more specifically for the treatment of inflammatory skins diseases, especially Netherton syndrome.
Applicant(s) SIXERA PHARMA AB
Representative Drug(s) D0P0OH Drug Info N.A. Click to Show More [1]
2 D01IXT Drug Info N.A. [1]
3 D00PVE Drug Info N.A. [1]
4 D05CJM Drug Info N.A. [1]
Patent ID US9695194
Title Benzoxazinone derivatives for treatment of skin diseases
Abstract The present invention relates to methods and compositions for inhibiting the activity of skin proteases, especially human kallikrein 7 (KLK7), human kallikrein 5 (KLK5), and human kallikrein 14 (KLK14). More specifically, the invention relates to the use of substituted 3,1-benzoxazin-4-ones being selective inhibitors of human skin kallikreins for the treatment of skin diseases, more specifically for the treatment of inflammatory skins diseases, especially Netherton syndrome.
Applicant(s) SIXERA PHARMA AB
Representative Drug(s) D0P0OH Drug Info N.A. Click to Show More [1]
2 D01IXT Drug Info N.A. [1]
3 D00PVE Drug Info N.A. [1]
4 D05CJM Drug Info N.A. [1]
References  Top
REF 1 Benzoxazinone derivatives for treatment of skin diseases. US9695194.

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