Patent(s) and the Corresponding Patented Drug(s) |
Top |
World Intellectual Property Organization (WIPO) |
Patent ID |
WO2015150612 |
Title |
Substituted Isatins and The Therapeutic Applications Thereof for The Treatment of Neurodegenerative Diseases. |
Abstract |
The invention relates to a family of differently substituted isatins that exhibit activity inhibiting the protein kinase with leucine-rich repeats (LRRK2), such that they are useful in the treatment of diseases mediated by said enzyme, such as inflammatory diseases, autoimmune diseases and neurodegenerative diseases, especially Parkinson's disease. |
Applicant(s) |
Consejo Superior Investigacion |
Representative Drug(s) |
D08WVK |
Drug Info
|
IC50 = 47 nM |
Click to Show More |
[1] |
2
|
D0QK7K
|
Drug Info
|
IC50 = 123 nM
|
[1] |
Patent ID |
WO2014170248 |
Title |
Arylpyrrolopyridine Derived Compounds As Lrrk2 Inhibitors. |
Abstract |
The present invention is directed to arylpyrrolopyridine derivatives of formula (A) (A). The compounds are considered useful for the treatment of diseases associated with LRRK2 such as Lewy body dementia, Parkinson's disease cancer. |
Applicant(s) |
H. Lundbeck A / S |
Representative Drug(s) |
D00FKF |
Drug Info
|
IC50 = 2 nM |
[1] |
Patent ID |
WO2014106612 |
Title |
Aminopyridine Derived Compounds As Lrrk2 Inhibitors. |
Abstract |
The present invention is directed to aminopyridine derived compounds of formula (A). The compounds are considered useful for the treatment of diseases associated with LRRK2 such a Lewy body dementia, Parkinson's disease or cancer. |
Applicant(s) |
H. Lundbeck A/S |
Representative Drug(s) |
D0D6DN |
Drug Info
|
IC50 = 95 nM |
[1] |