Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T09185 Target Info
Target Name Epithelial discoidin domain receptor 1 (DDR1)
Synonyms Tyrosine-protein kinase CAK; Tyrosine kinase DDR; TRKE; TRK E; RTK6; Protein-tyrosine kinase RTK-6; Protein-tyrosine kinase 3A; PTK3A; NTRK4; NEP; Mammary carcinoma kinase 10; MCK-10; HGK2; Epithelial discoidin domain-containing receptor 1; EDDR1; Discoidin receptor tyrosine kinase; Cell adhesion kinase; CD167a; CD167 antigen-like family member A
Target Type Patented-recorded Target
Gene Name DDR1
Biochemical Class Kinase
UniProt ID
DDR1_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9695118
Title Benzamide derivative
Abstract The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Applicant(s) Chugai Seiyaku Kabushiki Kaisha
Representative Drug(s) D0LL1P Drug Info IC50 = 9.7 nM Click to Show More [1]
2 D0ZK5P Drug Info IC50 = 29 nM [1]
3 D0DA4Y Drug Info IC50 = 140 nM [1]
Patent ID US9695118
Title Benzamide derivative
Abstract The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Applicant(s) Chugai Seiyaku Kabushiki Kaisha
Representative Drug(s) D0LL1P Drug Info IC50 = 9.7 nM Click to Show More [1]
2 D0ZK5P Drug Info IC50 = 29 nM [1]
3 D0DA4Y Drug Info IC50 = 140 nM [1]
Patent ID US9695118
Title Benzamide derivative
Abstract The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Applicant(s) Chugai Seiyaku Kabushiki Kaisha
Representative Drug(s) D0LL1P Drug Info IC50 = 9.7 nM Click to Show More [1]
2 D0ZK5P Drug Info IC50 = 29 nM [1]
3 D0DA4Y Drug Info IC50 = 140 nM [1]
Patent ID US9567304
Title Quinazolinedione derivative
Abstract The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Applicant(s) Chugai Seiyaku Kabushiki Kaisha
Representative Drug(s) D0H0GL Drug Info IC50 = 15 nM Click to Show More [2]
2 D00UAQ Drug Info IC50 = 22 nM [2]
3 D0Y3FD Drug Info IC50 = 43 nM [2]
Patent ID US9567304
Title Quinazolinedione derivative
Abstract The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Applicant(s) Chugai Seiyaku Kabushiki Kaisha
Representative Drug(s) D0H0GL Drug Info IC50 = 15 nM Click to Show More [2]
2 D00UAQ Drug Info IC50 = 22 nM [2]
3 D0Y3FD Drug Info IC50 = 43 nM [2]
Patent ID US9567304
Title Quinazolinedione derivative
Abstract The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Applicant(s) Chugai Seiyaku Kabushiki Kaisha
Representative Drug(s) D0H0GL Drug Info IC50 = 15 nM Click to Show More [2]
2 D00UAQ Drug Info IC50 = 22 nM [2]
3 D0Y3FD Drug Info IC50 = 43 nM [2]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0BW9L Drug Info IC50 = 5 nM [3]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0BW9L Drug Info IC50 = 5 nM [3]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0BW9L Drug Info IC50 = 5 nM [3]
Patent ID US9156852
Title Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
Abstract Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.
Applicant(s) HANMI PHARM. CO., LTD
Representative Drug(s) D0BW9L Drug Info IC50 = 5 nM [3]
Patent ID US8765747
Title Fused 2-aminothiazole compounds
Abstract The present application relates to therapeutic organic compounds of formula (I), wherein Q, R1, R2, R3, and R4 are defined herein. The invention also relates to pharmaceutical compositions comprising an effective amount of a therapeutic organic compound; and methods for treating and preventing disease such as cancer comprising administering and effective amount of a therapeutic organic compound to a subject in need thereof.
Applicant(s) Dana-Farber Cancer Institute, Inc.
Representative Drug(s) D0GT9T Drug Info N.A. [4]
References  Top
REF 1 Benzamide derivative. US9695118.
REF 2 Quinazolinedione derivative. US9567304.
REF 3 Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases. US9156852.
REF 4 Fused 2-aminothiazole compounds. US8765747.

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