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Target General Information |
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Target ID |
T08741 |
Target Info
|
Target Name |
Tyrosine-protein kinase CSK (CSK) |
Synonyms |
Protein-tyrosine kinase CYL; C-Src kinase |
Target Type |
Patented-recorded Target |
Gene Name |
CSK |
Biochemical Class |
Kinase |
UniProt ID |
|
Patent(s) and the Corresponding Patented Drug(s) |
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United States Patent and Trademark Office (USPTO) |
Patent ID |
US9278100 |
Title |
Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors |
Abstract |
Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors. |
Applicant(s) |
Pharmacyclics LLC |
Representative Drug(s) |
D02DJP |
Drug Info
|
IC50 = 2.4 nM |
[1] |
References |
Top |
REF 1 |
Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors. US9278100.
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