miRNA General Information
miRNA Mature ID hsa-miR-873-5p
miRNA Stemloop AC MI0005564
miRNA Stemloop ID hsa-mir-873
Sequence gcaggaacuugugagucuccu
TTD Target(s) Regulated by This miRNA Multidrug resistance protein 1 (ABCB1) Clinical trial Target Target Info [1]
Cyclin-dependent kinase 3 (CDK3) Clinical trial Target Target Info [2]
Protein(s) Regulated by This miRNA SRC kinase signaling inhibitor 1 Regulated Protein [3]
References
REF 1 MicroRNA-873 mediates multidrug resistance in ovarian cancer cells by targeting ABCB1. Tumour Biol. 2016 Aug;37(8):10499-506.
REF 2 MiR-873 regulates ER transcriptional activity and tamoxifen resistance via targeting CDK3 in breast cancer cells. Oncogene. 2015 Jul 23;34(30):3895-907.
REF 3 miR-873 induces lung adenocarcinoma cell proliferation and migration by targeting SRCIN1. Am J Transl Res. 2015 Nov 15;7(11):2519-26.

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