miRNA General Information
miRNA Mature ID hsa-miR-718
miRNA Stemloop AC MI0012489
miRNA Stemloop ID hsa-mir-718
Sequence cuuccgccccgccgggcgucg
TTD Target(s) Regulated by This miRNA Vascular endothelial growth factor A (VEGFA) Successful Target Target Info [1]
Phosphatase and tensin homolog (PTEN) Literature-reported Target Target Info [2]
Protein(s) Regulated by This miRNA Homeobox protein Hox-B8 Regulated Protein [3]
References
REF 1 MiR-718 represses VEGF and inhibits ovarian cancer cell progression. FEBS Lett. 2014 Jun 5;588(12):2078-86.
REF 2 HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway. Nucleic Acids Res. 2014 Sep;42(15):9862-79.
REF 3 Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation.Br J Cancer. 2015 Feb 3;112(3):532-8.

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