miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-657 | ||||
miRNA Stemloop AC | MI0003681 | ||||
miRNA Stemloop ID | hsa-mir-657 | ||||
Sequence | ggcagguucucacccucucuagg | ||||
TTD Target(s) Regulated by This miRNA | CI Man-6-P receptor (IGF2R) | Clinical trial Target | Target Info | [1] | |
Melanoma differentiation-associated protein 6 (CDKN1A) | Literature-reported Target | Target Info | [2] | ||
Protein(s) Regulated by This miRNA | Transducin-like enhancer protein 1 | Regulated Protein | [3] | ||
References | |||||
REF 1 | Allele-specific targeting of hsa-miR-657 to human IGF2R creates a potential mechanism underlying the association of ACAA-insertion/deletion polymorphism with type 2 diabetes. Biochem Biophys Res Commun. 2008 Sep 12;374(1):101-5. | ||||
REF 2 | Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. Oncogene. 2010 Apr 15;29(15):2302-8. | ||||
REF 3 | MicroRNA-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through nuclear factor kappa B pathways.Hepatology. 2013 May;57(5):1919-30. |
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