miRNA General Information
miRNA Mature ID hsa-miR-605-5p
miRNA Stemloop AC MI0003618
miRNA Stemloop ID hsa-mir-605
Sequence uaaaucccauggugccuucuccu
TTD Target(s) Regulated by This miRNA Ubiquitin-protein ligase E3 Mdm2 (MDM2) Clinical trial Target Target Info [1]
Cellular tumor antigen p53 (TP53) Clinical trial Target Target Info [1]
Gankyrin (PSMD10) Literature-reported Target Target Info [2]
Protein(s) Regulated by This miRNA Protein transport protein Sec24D Regulated Protein [3]
Transcription elongation factor A protein-like 1 Regulated Protein [1]
References
REF 1 miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress. EMBO J. 2011 Feb 2;30(3):524-32.
REF 2 MiR-605 represses PSMD10/Gankyrin and inhibits intrahepatic cholangiocarcinoma cell progression. FEBS Lett. 2014 Sep 17;588(18):3491-500.
REF 3 New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites.Genome Res. 2009 Jul;19(7):1175-83.
REF 4 miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress. EMBO J. 2011 Feb 2;30(3):524-32.

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