miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-544a | ||||
miRNA Stemloop AC | MI0003515 | ||||
miRNA Stemloop ID | hsa-mir-544a | ||||
Sequence | auucugcauuuuuagcaaguuc | ||||
TTD Target(s) Regulated by This miRNA | Signal transducer and activator of transcription 3 (STAT3) | Successful Target | Target Info | [1] | |
Polycomb complex protein BMI-1 (BMI1) | Clinical trial Target | Target Info | [2] | ||
Epithelial cadherin (CDH1) | Literature-reported Target | Target Info | [3] | ||
Protein(s) Regulated by This miRNA | B-cell lymphoma 6 protein | Regulated Protein | [1] | ||
Homeobox protein Hox-A10 | Regulated Protein | [5] | |||
References | |||||
REF 1 | MicroRNA-544 down-regulates both Bcl6 and Stat3 to inhibit tumor growth of human triple negative breast cancer. Biol Chem. 2016 Oct 1;397(10):1087-95. | ||||
REF 2 | MicroRNAs in the imprinted DLK1-DIO3 region repress the epithelial-to-mesenchymal transition by targeting the TWIST1 protein signaling network. J Biol Chem. 2012 Dec 14;287(51):42695-707. | ||||
REF 3 | miR-544a promotes the invasion of lung cancer cells by targeting cadherina 1 in vitro. Onco Targets Ther. 2014 Jun 4;7:895-900. | ||||
REF 4 | MicroRNA-544 down-regulates both Bcl6 and Stat3 to inhibit tumor growth of human triple negative breast cancer. Biol Chem. 2016 Oct 1;397(10):1087-95. | ||||
REF 5 | MicroRNA-544a Regulates Migration and Invasion in Colorectal Cancer Cells via Regulation of Homeobox A10.Dig Dis Sci. 2016 Sep;61(9):2535-44. |
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