miRNA General Information
miRNA Mature ID hsa-miR-524-5p
miRNA Stemloop AC MI0003160
miRNA Stemloop ID hsa-mir-524
Sequence cuacaaagggaagcacuuucuc
TTD Target(s) Regulated by This miRNA Matrix metalloproteinase-2 (MMP-2) Successful Target Target Info [1]
Matrix metalloproteinase-9 (MMP-9) Clinical trial Target Target Info [1]
Cyclin-dependent kinase 2 (CDK2) Clinical trial Target Target Info [2]
Wee1-like protein kinase (WEE1) Clinical trial Target Target Info [2]
Dual specificity protein kinase TTK (MPS1) Clinical trial Target Target Info [2]
Protein(s) Regulated by This miRNA Protein jagged-1 Regulated Protein [3]
Transcription factor HES-1 Regulated Protein [3]
Transcription factor SOX-9 Regulated Protein [4]
References
REF 1 MicroRNA-524-5p suppresses the growth and invasive abilities of gastric cancer cells. Oncol Lett. 2016 Mar;11(3):1926-1932.
REF 2 Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression. Nucleic Acids Res. 2013 Dec;41(22):e203.
REF 3 The putative tumor suppressor miR-524-5p directly targets Jagged-1 and Hes-1 in glioma.Carcinogenesis. 2012 Nov;33(11):2276-82.
REF 4 Upregulation of microRNA-524-5p enhances the cisplatin sensitivity of gastric cancer cells by modulating proliferation and metastasis via targeting SOX9.Oncotarget. 2017 Jan 3;8(1):574-582.

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