miRNA General Information
miRNA Mature ID hsa-miR-520a-3p
miRNA Stemloop AC MI0003149
miRNA Stemloop ID hsa-mir-520a
Sequence aaagugcuucccuuuggacugu
TTD Target(s) Regulated by This miRNA G1/S-specific cyclin-D1 (CCND1) Clinical trial Target Target Info [1]
MAPK/ERK kinase kinase 2 (MAP3K2) Clinical trial Target Target Info [2]
TGF-beta receptor type II (TGFBR2) Clinical trial Target Target Info [3]
Extracellular matrix receptor III (CD44) Clinical trial Target Target Info [1]
Melanoma differentiation-associated protein 6 (CDKN1A) Literature-reported Target Target Info [4]
Protein(s) Regulated by This miRNA ATP-dependent 6-phosphofructokinase, platelet type Regulated Protein [5]
Homeobox protein Hox-D8 Regulated Protein [6]
References
REF 1 Suppressing role of miR-520a-3p in breast cancer through CCND1 and CD44. Am J Transl Res. 2017 Jan 15;9(1):146-154.
REF 2 The microRNA-520a-3p inhibits proliferation, apoptosis and metastasis by targeting MAP3K2 in non-small cell lung cancer. Am J Cancer Res. 2015 Jan 15;5(2):802-11.
REF 3 MicroRNA-520c inhibits glioma cell migration and invasion by the suppression of transforming growth factor- receptor type2. Oncol Rep. 2017 Mar;37(3):1691-1697.
REF 4 Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. Oncogene. 2010 Apr 15;29(15):2302-8.
REF 5 Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520.Hepatology. 2013 Jul;58(1):182-91.
REF 6 microRNA-520a-3p inhibits proliferation and cancer stem cell phenotype by targeting HOXD8 in non-small cell lung cancer.Oncol Rep. 2016 Dec;36(6):3529-3535.

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