miRNA Details
| miRNA General Information | |||||
|---|---|---|---|---|---|
| miRNA Mature ID | hsa-miR-505-3p | ||||
| miRNA Stemloop AC | MI0003190 | ||||
| miRNA Stemloop ID | hsa-mir-505 | ||||
| Sequence | cgucaacacuugcugguuuccu | ||||
| TTD Target(s) Regulated by This miRNA | Transforming growth factor alpha (TGFA) | Clinical trial Target | Target Info | [1] | |
| Gankyrin (PSMD10) | Literature-reported Target | Target Info | [2] | ||
| Protein(s) Regulated by This miRNA | E3 ubiquitin-protein ligase AMFR | Regulated Protein | [3] | ||
| Serine/arginine-rich splicing factor 1 | Regulated Protein | [4] | |||
| References | |||||
| REF 1 | MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-. Mol Cancer. 2016 Feb 2;15:11. | ||||
| REF 2 | Association between functional PSMD10 Rs111638916 variant regulated by MiR-505 and gastric cancer risk in a Chinese population. Cell Physiol Biochem. 2015;37(3):1010-7. | ||||
| REF 3 | MicroRNAs Provide Feedback Regulation of Epithelial-Mesenchymal Transition Induced by Growth Factors.J Cell Physiol. 2016 Jan;231(1):120-9. | ||||
| REF 4 | MicroRNA (miRNA)-mediated interaction between leukemia/lymphoma-related factor (LRF) and alternative splicing factor/splicing factor 2 (ASF/SF2) affects mouse embryonic fibroblast senescence and apoptosis.J Biol Chem. 2010 Dec 10;285(50):39551-63. | ||||
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