miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-494-5p | ||||
miRNA Stemloop AC | MI0003134 | ||||
miRNA Stemloop ID | hsa-mir-494 | ||||
Sequence | agguuguccguguugucuucucu | ||||
TTD Target(s) Regulated by This miRNA | C-X-C chemokine receptor type 4 (CXCR4) | Successful Target | Target Info | [1] | |
Dihydrothymine dehydrogenase (DPYD) | Successful Target | Target Info | [2] | ||
Phosphatase and tensin homolog (PTEN) | Literature-reported Target | Target Info | [3] | ||
References | |||||
REF 1 | miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/-catenin signaling pathway. Oncol Rep. 2015 Jul;34(1):525-31. | ||||
REF 2 | MicroRNA-494 sensitizes colon cancer cells to fluorouracil through regulation of DPYD. IUBMB Life. 2015 Mar;67(3):191-201. | ||||
REF 3 | miR-494 promotes cell proliferation, migration and invasion, and increased sorafenib resistance in hepatocellular carcinoma by targeting PTEN. Oncol Rep. 2015 Aug;34(2):1003-10. |
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