miRNA General Information
miRNA Mature ID hsa-miR-487b-3p
miRNA Stemloop AC MI0003530
miRNA Stemloop ID hsa-mir-487b
Sequence aaucguacagggucauccacuu
TTD Target(s) Regulated by This miRNA Metabotropic glutamate receptor 3 (mGluR3) Clinical trial Target Target Info [1]
Thrombospondin-1 (THBS1) Clinical trial Target Target Info [2]
Proto-oncogene c-Myc (MYC) Literature-reported Target Target Info [3]
Polycomb complex protein BMI-1 (BMI1) Clinical trial Target Target Info [3]
Wnt-5a protein (WNT5A) Literature-reported Target Target Info [3]
Protein(s) Regulated by This miRNA Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Regulated Protein [4]
Polycomb protein SUZ12 Regulated Protein [3]
References
REF 1 The miR-487b-3p/GRM3/TGF signaling axis is an important regulator of colon cancer tumorigenesis. Oncogene. 2017 Jun 15;36(24):3477-3489.
REF 2 miR-487b promotes human umbilical vein endothelial cell proliferation, migration, invasion and tube formation through regulating THBS1. Neurosci Lett. 2015 Mar 30;591:1-7.
REF 3 Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis. J Clin Invest. 2013 Mar;123(3):1241-61.
REF 4 MiR-134/487b/655 cluster regulates TGF--induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells.Mol Cancer Ther. 2014 Feb;13(2):444-53.
REF 5 Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis. J Clin Invest. 2013 Mar;123(3):1241-61.

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