miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-485-5p | ||||
miRNA Stemloop AC | MI0002469 | ||||
miRNA Stemloop ID | hsa-mir-485 | ||||
Sequence | agaggcuggccgugaugaauuc | ||||
TTD Target(s) Regulated by This miRNA | Cellular tumor antigen p53 (TP53) | Clinical trial Target | Target Info | [1] | |
Frizzled-7 receptor (FZD7) | Clinical trial Target | Target Info | [2] | ||
High mobility group protein HMGI-C (HMGA2) | Literature-reported Target | Target Info | [3] | ||
Stanniocalcin-2 (STC2) | Literature-reported Target | Target Info | [4] | ||
Protein(s) Regulated by This miRNA | Apolipoprotein A-V | Regulated Protein | [5] | ||
Flotillin-1 | Regulated Protein | [6] | |||
Hypoxia-inducible factor 3-alpha | Regulated Protein | [7] | |||
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | Regulated Protein | [8] | |||
References | |||||
REF 1 | Negative regulation of tumor suppressor p53 by microRNA miR-504. Mol Cell. 2010 Jun 11;38(5):689-99. | ||||
REF 2 | MicroRNA-485-5p represses melanoma cell invasion and proliferation by suppressing Frizzled7. Biomed Pharmacother. 2017 Jun;90:303-310. | ||||
REF 3 | miR 85 p inhibits bladder cancer metastasis by targeting HMGA2. Int J Mol Med. 2015 Oct;36(4):1136-42. | ||||
REF 4 | MicroRNA-485-5p suppresses cell proliferation and invasion in hepatocellular carcinoma by targeting stanniocalcin 2. Int J Clin Exp Pathol. 2015 Oct 1;8(10):12292-9. | ||||
REF 5 | An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site.Am J Hum Genet. 2014 Jan 2;94(1):129-34. | ||||
REF 6 | miR-485-5p acts as a negative regulator in gastric cancer progression by targeting flotillin-1. Am J Transl Res. 2015 Nov 15;7(11):2212-22. | ||||
REF 7 | MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3.BMC Cancer. 2014 Jun 13;14:429. | ||||
REF 8 | MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1 expression.Cell Death Dis. 2016 Mar 24;7:e2159. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.