miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-433-5p | ||||
miRNA Stemloop AC | MI0001723 | ||||
miRNA Stemloop ID | hsa-mir-433 | ||||
Sequence | uacggugagccugucauuauuc | ||||
TTD Target(s) Regulated by This miRNA | Osteonectin (SPARC) | Literature-reported Target | Target Info | [1] | |
Protein(s) Regulated by This miRNA | Glutamate--cysteine ligase catalytic subunit | Regulated Protein | [2] | ||
Glutamate--cysteine ligase regulatory subunit | Regulated Protein | [2] | |||
References | |||||
REF 1 | A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433. J Bone Miner Res. 2015 Apr;30(4):723-32. | ||||
REF 2 | Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF--Dependent Fibrogenesis.Antioxid Redox Signal. 2015 Nov 10;23(14):1092-105. |
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