miRNA General Information
miRNA Mature ID hsa-miR-383-5p
miRNA Stemloop AC MI0000791
miRNA Stemloop ID hsa-mir-383
Sequence agaucagaaggugauuguggcu
TTD Target(s) Regulated by This miRNA Insulin-like growth factor I receptor (IGF1R) Successful Target Target Info [1]
Vascular endothelial growth factor A (VEGFA) Successful Target Target Info [2]
Iodothyronine deiodinase type I (DIO1) Successful Target Target Info [3]
G1/S-specific cyclin-D1 (CCND1) Clinical trial Target Target Info [4]
Serine/threonine-protein kinase ATR (FRP1) Clinical trial Target Target Info [5]
A proliferation-inducing ligand (APRIL) Clinical trial Target Target Info [6]
Interferon regulatory factor 1 (IRF1) Literature-reported Target Target Info [7]
Protein(s) Regulated by This miRNA Serine/threonine-protein phosphatase 1 regulatory subunit 10 Regulated Protein [8]
Thioredoxin-dependent peroxide reductase, mitochondrial Regulated Protein [9]
References
REF 1 Downregulation of miR-383 promotes glioma cell invasion by targeting insulin-like growth factor 1 receptor. Med Oncol. 2013;30(2):557.
REF 2 The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation. PLoS One. 2008 Mar 5;3(3):e1719.
REF 3 MiR-224 targets the 3'UTR of type 1 5'-iodothyronine deiodinase possibly contributing to tissue hypothyroidism in renal cancer. PLoS One. 2011;6(9):e24541.
REF 4 The targeting and functions of miRNA-383 are mediated by FMRP during spermatogenesis. Cell Death Dis. 2013 May 2;4:e617.
REF 5 STAT3 regulated ATR via microRNA-383 to control DNA damage to affect apoptosis in A431 cells. Cell Signal. 2015 Nov;27(11):2285-95.
REF 6 miR-383 inhibits hepatocellular carcinoma cell proliferation via targeting APRIL. Tumour Biol. 2016 Feb;37(2):2497-507.
REF 7 Downregulation of microRNA-383 is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation by targeting IRF1. Cell Death Dis. 2010 Nov 4;1:e94.
REF 8 microRNA-383 impairs phosphorylation of H2AX by targeting PNUTS and inducing cell cycle arrest in testicular embryonal carcinoma cells.Cell Signal. 2014 May;26(5):903-11.
REF 9 MiR-383 is downregulated in medulloblastoma and targets peroxiredoxin 3 (PRDX3).Brain Pathol. 2013 Jul;23(4):413-25.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.