miRNA General Information
miRNA Mature ID hsa-miR-381-3p
miRNA Stemloop AC MI0000789
miRNA Stemloop ID hsa-mir-381
Sequence uauacaagggcaagcucucugu
TTD Target(s) Regulated by This miRNA Calcium-dependent chloride channel anoctamin (ANO) Successful Target Target Info [1]
Histone deacetylase 4 (HDAC4) Clinical trial Target Target Info [2]
Wee1-like protein kinase (WEE1) Clinical trial Target Target Info [3]
Gap junction alpha-1 protein (GJA1) Clinical trial Target Target Info [4]
Protein(s) Regulated by This miRNA NF-kappa-B inhibitor alpha Regulated Protein [5]
P2X purinoceptor 5 Regulated Protein [6]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Regulated Protein [7]
T-cell surface glycoprotein CD1c Regulated Protein [8]
TBC1 domain family member 9 Regulated Protein [9]
Twist-related protein 1 Regulated Protein [10]
References
REF 1 MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression. J Exp Clin Cancer Res. 2017 Feb 13;36(1):29.
REF 2 MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression. Int J Mol Sci. 2016 Aug 23;17(9). pii: E1377.
REF 3 Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 2013 Mar 21;495(7441):333-8.
REF 4 Identification of miR-200a as a novel suppressor of connexin 43 in breast cancer cells. Biosci Rep. 2015 Aug 17;35(5). pii: e00251.
REF 5 Increased miR-381a-3p Contributes to Osteoarthritis by Targeting IkB.Ann Clin Lab Sci. 2016 May;46(3):247-53.
REF 6 MicroRNA-381 suppresses cell growth and invasion by targeting the liver receptor homolog-1 in hepatocellular carcinoma.Oncol Rep. 2016 Mar;35(3):1831-40.
REF 7 SMARCB1 expression in epithelioid sarcoma is regulated by miR-206, miR-381, and miR-671-5p on Both mRNA and protein levels.Genes Chromosomes Cancer. 2014 Feb;53(2):168-76.
REF 8 MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.J Immunol. 2016 Jul 15;197(2):580-9.
REF 9 Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance.PLoS One. 2013 Nov 26;8(11):e82062.
REF 10 MiR-381 functions as a tumor suppressor in colorectal cancer by targeting Twist1.Onco Targets Ther. 2016 Mar 7;9:1231-9.

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