miRNA General Information
miRNA Mature ID hsa-miR-30c-2-3p
miRNA Stemloop AC MI0000254
miRNA Stemloop ID hsa-mir-30c-2
Sequence cugggagaaggcuguuuacucu
TTD Target(s) Regulated by This miRNA G1/S-specific cyclin-E1 (CCNE1) Literature-reported Target Target Info [1]
Cyclic-AMP-dependent transcription factor ATF-3 (ATF3) Literature-reported Target Target Info [2]
Protein(s) Regulated by This miRNA B-cell CLL/lymphoma 9 protein Regulated Protein [3]
Tumor necrosis factor receptor type 1-associated DEATH domain protein Regulated Protein [1]
Zinc finger protein SNAI1 Regulated Protein [5]
References
REF 1 MicroRNA-30c-2-3p negatively regulates NF-B signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Mol Oncol. 2015 Jun;9(6):1106-19.
REF 2 Lysophosphatidic Acid Mediates Activating Transcription Factor 3 Expression Which Is a Target for Post-Transcriptional Silencing by miR-30c-2-3p. PLoS One. 2015 Sep 29;10(9):e0139489.
REF 3 MicroRNA-30c-2* expressed in ovarian cancer cells suppresses growth factor-induced cellular proliferation and downregulates the oncogene BCL9.Mol Cancer Res. 2011 Dec;9(12):1732-45.
REF 4 MicroRNA-30c-2-3p negatively regulates NF-B signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Mol Oncol. 2015 Jun;9(6):1106-19.
REF 5 MiR-30c protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition in db/db mice.Aging Cell. 2017 Apr;16(2):387-400.

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