miRNA General Information
miRNA Mature ID hsa-miR-30a-3p
miRNA Stemloop AC MI0000088
miRNA Stemloop ID hsa-mir-30a
Sequence cuuucagucggauguuugcagc
TTD Target(s) Regulated by This miRNA Cyclin-dependent kinase 6 (CDK6) Successful Target Target Info [1]
Notch-1 receptor (NOTCH1) Clinical trial Target Target Info [2]
Thrombospondin-1 (THBS1) Clinical trial Target Target Info [1]
Beclin-1 (BECN1) Literature-reported Target Target Info [3]
Cyclic-AMP-dependent transcription factor ATF-3 (ATF3) Literature-reported Target Target Info [4]
Cysteine-rich angiogenic inducer 61 (CYR61) Literature-reported Target Target Info [1]
Methyl cpg binding protein 2 (MECP2) Clinical trial Target Target Info [5]
Runt-related transcription factor 2 (RUNX2) Literature-reported Target Target Info [6]
Protein(s) Regulated by This miRNA Cell surface hyaluronidase Regulated Protein [1]
Keratin, type II cytoskeletal 7 Regulated Protein [8]
Nuclear factor of activated T-cells, cytoplasmic 3 Regulated Protein [9]
Tubulin alpha-1A chain Regulated Protein [1]
Vezatin Regulated Protein [1]
WD repeat-containing protein 82 Regulated Protein [1]
X-box-binding protein 1 Regulated Protein [10]
Y+L amino acid transporter 2 Regulated Protein [1]
References
REF 1 Physiological identification of human transcripts translationally regulated by a specific microRNA. Hum Mol Genet. 2005 Dec 15;14(24):3813-21.
REF 2 A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies. Leukemia. 2015 Apr;29(4):968-76.
REF 3 MiRNA-30a-mediated autophagy inhibition sensitizes renal cell carcinoma cells to sorafenib. Biochem Biophys Res Commun. 2015 Apr 3;459(2):234-239.
REF 4 miRNA expression pattern associated with prognosis in elderly patients with advanced OPSC and OCC. Int J Oncol. 2013 Sep;43(3):839-49.
REF 5 MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses. Circ Res. 2013 Sep 27;113(8):997-1003.
REF 6 The overexpression of miR-30a affects cell proliferation of chondrosarcoma via targeting Runx2. Tumour Biol. 2016 May;37(5):5933-40.
REF 7 Physiological identification of human transcripts translationally regulated by a specific microRNA. Hum Mol Genet. 2005 Dec 15;14(24):3813-21.
REF 8 Identification of novel microRNA targets based on microRNA signatures in bladder cancer.Int J Cancer. 2009 Jul 15;125(2):345-52.
REF 9 MiR-30a Inhibits the Epithelial--Mesenchymal Transition of Podocytes through Downregulation of NFATc3.Int J Mol Sci. 2015 Oct 12;16(10):24032-47.
REF 10 MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo.J Transl Med. 2015 Nov 16;13:363.

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